Director, Portfolio Strategy - Global Initiatives
Cambridge, United States
June 6, 2026
Northeast
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About This Role
Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. The firm brings together the greatest scientific minds with entrepreneurial company builders and capital to allow courageous leaps in human health, sustainability, and beyond. Flagship has been recognized twice on FORTUNE's 'Change the World' list and four times on Fast Company's World's Most Innovative Companies.
The Director, Portfolio Strategy - Global Initiatives is a high-impact role at the intersection of science, strategy, and business, focused on shaping and advancing a differentiated BioMedicines R&D portfolio from early discovery through clinical development and commercialization readiness.
The role partners closely with senior BioMedicines and Flagship Pioneering leadership to define portfolio direction, build new R&D programs, and drive high-stakes investment and prioritization decisions. The successful candidate will work hands-on with scientific leaders, internal venture teams, and partnering colleagues to translate complex science into clear strategies.
Key Responsibilities:
- Shape and advance the BioMedicines R&D portfolio from early discovery through clinical development
- Partner with senior leadership to define portfolio direction and build new R&D programs
- Drive investment and prioritization decisions across the portfolio
- Work collaboratively with scientific leaders and internal venture teams
- Translate complex scientific insights into clear strategic recommendations
Qualifications:
- Deep experience in life sciences strategy, biotech, or venture capital/private equity in the healthcare sector
- Strong ability to synthesize scientific and business information into clear investment recommendations
- Experience working within or alongside a major life sciences company or investment firm
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