March Startup Funding: AI, Healthtech, SaaS Raise Big

March 2026 marked a significant influx of capital into the U.S. startup arena, with multiple companies securing substantial funding rounds exceeding $100 million. This period highlights investor confidence in sectors ranging from artificial intelligence and advanced healthcare solutions to critical enterprise software infrastructure.

Leading the charge in the AI domain, XBOW, a Seattle-based firm specializing in autonomous security testing software, secured a $120 million Series C. Founded in 2024 by Oege de Moor, XBOW's technology identifies and validates vulnerabilities in digital systems. The round saw participation from prominent investors including Sequoia Capital, Northzone, DFJ Growth, Altimeter Capital, NFDG Ventures, Alkeon Capital, and Sofina, underscoring the growing demand for sophisticated cybersecurity solutions. XBOW has now amassed a total of $237 million in equity funding.

In the healthcare sector, Imperative Care, based in Campbell, announced a substantial $100 million venture round. This company, established in 2015 by Nick Hopkins, is dedicated to addressing critical unmet needs in stroke treatment. The significant capital infusion was supported by a robust syndicate of investors such as Perceptive Advisors, Catalio Capital Management, Bain Capital Life Sciences, Ally Bridge Group, Elevage Medical Technologies, Brown Advisory, Longaeva Partners, and Perceptive Advisors. Imperative Care's total funding now stands at an impressive $519 million, reflecting strong backing for its innovative medical devices and approaches.

The enterprise software and developer tools space also saw major activity. WorkOS, a San Francisco-based company providing a unified platform with modern APIs and SDKs for enterprise-ready features, closed a $100 million Series C. Founded in 2019 by Michael Grinich, WorkOS has garnered support from a diverse group of investors including Lightspeed Venture Partners, Craft Ventures, Sapphire Ventures, Ballistic Ventures, SV Angel, Abstract, Audacious Ventures, Greenoaks, Meritech Capital Partners. This brings their total equity raised to $195 million, signaling continued growth in the developer infrastructure market.

Further demonstrating the breadth of investment interest, ORO Labs, an AI-powered procurement orchestration platform, raised $100 million in its Series C. The Palo Alto-based company, founded in 2020 by Lalitha Rajagopalan, Sudhir Bhojwani, and Yuan Tung, aims to enhance organizational efficiency. Key investors in this round included B Capital, Norwest, Felicis, XYZ Venture Capital, Brighton Park Capital, and Goldman Sachs Growth Equity. ORO Labs has now secured a total of $159 million, highlighting the increasing adoption of AI in business operations.

Other notable large rounds included Bluesky, a social media network, which secured $100 million in Series B funding from investors like Alumni Ventures, Automattic, True Ventures, Blockchain Capital, and Protocol Labs. Cape, a privacy-enabling technology firm, also closed a $100 million Series C round with backing from Andreessen Horowitz, IVP, Bain Capital Ventures, A*, and XYZ Venture Capital. Additionally, Performance Drone Works, focused on autonomous unmanned aerial systems, received $110 million in Series B funding from investors such as Gaingels, Lux Capital, Ondas Networks, Booz Allen Hamilton, and Squadra Ventures.

These substantial funding events in March underscore a dynamic investment climate, particularly for companies leveraging advanced technologies like AI and those addressing critical needs in healthcare and enterprise efficiency. The consistent flow of capital into these sectors suggests a strategic focus on innovation and scalable solutions poised to shape future market dynamics.