Healthtech Investors in North America

137 Ventures is a San Francisco‑based private investment firm specializing in providing liquidity solutions and growth capital to founders, early employees and angel investors in high‑growth technology companies. Founded in 2011, the firm manages over US$5 billion across funds that purchase private company shares on the secondary market and participate in primary growth rounds. 137’s approach allows early stakeholders to realize liquidity without forcing a premature sale or IPO, while enabling companies to continue compounding value privately. Its portfolio includes some of Silicon Valley’s most iconic names in enterprise software, fintech, consumer internet and mobility. In addition to capital, the firm offers strategic support, including introductions to later‑stage investors, guidance on secondary market dynamics and advice on navigating complex cap‑table structures. The team maintains strict confidentiality and aims to align with both founders and early shareholders by structuring transactions that work for all parties. 137 Ventures’ culture emphasizes long‑term thinking, integrity and the belief that providing liquidity at the right time can be a catalyst for innovation, allowing founders and employees to focus on building rather than managing personal finances.

1Flourish Capital is a venture capital firm focused on investing in early-stage, disruptive technology startups led by founders of high character who are on missions to advance human flourishing. Beyond providing capital, 1Flourish actively supports its portfolio companies through strategic guidance, leadership training, and cultivating exceptional company cultures based on principles such as trust, humility, and accountability. Their approach emphasizes building enduring values and sustainable success in their investments. The firm leverages the expertise of advisors like Patrick Lencioni and The Table Group to help founders develop strong leadership and governance practices. 1Flourish’s team has extensive experience managing over $1 billion in venture capital and private equity, with backgrounds including serial entrepreneurship, technology leadership, and operational excellence. This deep operational and investment experience enables them to nurture portfolio companies effectively. 1Flourish primarily invests in the United States, focusing on sectors such as e-commerce and enterprise technology. Their investment style is collaborative and operator-led, emphasizing disciplined scaling of innovative businesses. The firm is known for its commitment to principled leadership and high-performance company cultures, aiming to back visionary technical founders poised to scale solutions that enhance human well-being.

8VC is a technology and life‑sciences venture capital firm founded in 2015 by Joe Lonsdale, Drew Oetting, Alex Kolicich, and Jake Medwell. Originating in San Francisco and now headquartered in Austin, Texas, the firm brings together operators, technologists, and policy thinkers to invest in startups built to solve deep infrastructure and societal challenges. With over $6 billion in committed capital and a portfolio of more than 350 companies, 8VC invests across pre‑seed through growth stages in areas such as logistics, defense, enterprise software, healthcare, life sciences, manufacturing, financial services, and IT infrastructure. The firm also operates a proprietary “Build” program to launch new companies and a fellowship to attract top talent to its portfolio. Driven by a mission to "fix a broken world," 8VC backs transformative entrepreneurs building long‑term value in sectors often overlooked or deeply entrenched. Notable investments include Anduril, Epirus, Palantir, Guardant Health, and Hyperloop One, reflecting the firm’s belief in principled contrarianism and societal impact.

ACME Capital is a forward-thinking venture capital firm dedicated to supporting early-stage startups that are building transformative technologies. With a focus on bold entrepreneurs and disruptive ideas, ACME Capital partners with founders from seed to growth stages, providing capital, strategic insight, and long-term support. The firm is deeply rooted in Silicon Valley’s innovation ecosystem and operates with a global outlook. The firm has developed a strong track record of successful investments across frontier technology, enterprise software, and digital platforms. ACME Capital prioritizes ventures that demonstrate scalable potential, technical depth, and the ability to fundamentally improve industries. Its portfolio includes a mix of trailblazing companies that are redefining sectors like AI, robotics, cybersecurity, and digital health. ACME Capital’s team brings together decades of operational experience, domain expertise, and a collaborative approach to venture investing. Beyond financial backing, the firm acts as a hands-on partner to its portfolio companies, offering guidance on product development, go-to-market strategies, and follow-on fundraising. By staying agile and founder-focused, ACME Capital continues to identify the next generation of global leaders in tech.

Andreessen Horowitz, also known as a16z and legally AH Capital Management, LLC, is a privately held venture capital firm headquartered in Menlo Park, California. It was founded on July 6, 2009, by tech visionaries Marc Andreessen and Ben Horowitz, initially as a $300 million seed fund. From humble beginnings, it rapidly scaled to become one of Silicon Valley’s most influential VC outfits. The firm manages approximately $42 billion in assets as of May 2024—but more recent reporting points to roughly $45 billion in committed capital by April 2025. A16z’s hallmark is an operationally focused investment model: beyond funding, it offers founders access to deep networks, strategic support, talent, and infrastructure. The firm frequently structures dedicated funds across sectors like cryptocurrency, biotechnology, generative AI, gaming, and what it terms ‘American Dynamism’ (defense and industrial tech). As a stage‑agnostic investor, a16z participates in seed rounds as well as late-stage and growth financing across multiple verticals: AI infrastructure and applications, consumer platforms, fintech services, healthcare and bio tech, enterprise IT (cloud, security, SaaS), gaming, and education. The firm also recently pursued a record $20 billion megafund focused on growth‑stage AI startups in the U.S., underscoring its ambition in catalyzing emerging tech leaders.

Animal Capital is a venture capital firm headquartered in New York City and Los Angeles, California, founded by TikTok influencers including Josh Richards, Griffin Johnson, and Noah Beck. The firm specializes in investing in early-stage companies with a focus on Generation Z consumers, leveraging proprietary marketing channels and social media influence to drive growth and consumer awareness.The firm manages a $15 million fund, Animal Capital Fund I, which primarily targets investments in the consumer products and services, financial technology, health and wellness, and media sectors. Animal Capital invests mainly in the United States, focusing on companies in sectors such as CPG/D2C, Web3/crypto, marketplaces, ecommerce, communications and information technology, and life sciences.Animal Capital typically invests in pre-seed, seed, and Series A rounds, with check sizes ranging from $100K to $1M. The firm combines traditional venture capital services with a unique ability to influence a new generation of consumers through its founders' social media reach. The team includes key partners such as Josh Richards (Founder and Operating Partner), Griffin Johnson (General Partner), Dylann Sands (Partner), and Marshall Sandman (Managing Partner).

Atlantic Vantage Point (AVP), formerly AXA Venture Partners, is a global investment platform that became independent in 2024 following a management buyout from AXA. Founded in 2016, the firm focuses on supporting high-growth technology companies across various stages of development. With newfound strategic autonomy, AVP continues to foster innovation while preserving its legacy of institutional strength. AVP manages over €2.5 billion in assets through four core strategies: venture, early growth, growth, and fund of funds. The firm invests in enterprise software, fintech, digital health, cybersecurity, and consumer tech sectors. Its expansion team works closely with portfolio companies to provide strategic support, industry access, and scale-up capabilities. With offices in Paris, London, and New York, AVP leverages its transatlantic footprint to identify and nurture the next generation of tech leaders. Flagship initiatives like the €1.5 billion Growth Fund I, backed by AXA and the European Investment Fund, underscore AVP’s mission to accelerate technology innovation on a global scale.

Avenir Growth Capital is a New York‑based growth equity firm that focuses on scaling technology‑enabled businesses. Founded in 2017 by Andrew Sugrue and Jamie Reynolds, Avenir operates with the belief that durable companies are built over decades, not quarters. The firm typically invests between US$25 million and US$150 million in companies that have established product‑market fit and are seeking capital to accelerate expansion, enter new markets or execute strategic acquisitions. Avenir manages roughly US$2 billion across several funds and works closely with management teams to refine go‑to‑market strategy, align organizational incentives and recruit senior talent. Its portfolio spans sectors such as B2B software, financial services, education, healthcare technology and consumer marketplaces. The firm’s investment philosophy prioritizes sustainable growth and long‑term value over short‑term hype, often maintaining ownership stakes for many years. Avenir’s partners bring experience from private equity, growth investing and operational leadership, enabling them to serve as sounding boards and connectors for founders. They also place a premium on culture, partnering only with businesses that demonstrate integrity, transparency and a mission‑driven ethos.

Bosch Ventures, officially known as Robert Bosch Venture Capital GmbH (RBVC), is the corporate venture capital arm of the Bosch Group. Established in 2007, RBVC invests globally in innovative startups across all stages of development, focusing on technologies that are strategically significant to Bosch's future. RBVC's investment portfolio encompasses sectors such as automation, electrification, energy efficiency, enabling technologies, and healthcare systems. By leveraging Bosch's extensive global network and industry expertise, RBVC provides not only capital but also strategic support to its portfolio companies, fostering growth and innovation. With offices in Germany, the United States, Israel, and China, RBVC maintains a strong international presence. The firm typically invests between €500,000 and €10 million per company, with total assets under management exceeding €200 million.

Founded in 2019 by veteran investor John Kim, Brewer Lane Ventures is a Boston-based venture capital firm specializing in early-stage investments within the fintech and insurtech sectors. The firm partners with visionary entrepreneurs who are reimagining how consumers and businesses engage with financial services and insurance, aiming to drive innovation and efficiency in these industries. Brewer Lane Ventures leverages its extensive industry knowledge and networks to provide strategic guidance and support to its portfolio companies. The firm's investment strategy focuses on backing startups that are developing cutting-edge solutions in areas such as digital health, wealth management, payments, and risk assessment. Notable investments include companies like Empathy, January, and Codoxo, which are at the forefront of transforming their respective fields. With a hands-on approach, Brewer Lane Ventures is committed to helping its portfolio companies scale and succeed. The firm's dedication to fostering innovation and supporting entrepreneurs positions it as a key player in the venture capital landscape, particularly within the financial services and insurance sectors.

Founded in 2015 by Mingpo Cai and Denis Barrier, Cathay Innovation is a global venture capital firm affiliated with Cathay Capital. The firm focuses on multi-stage investments in innovative startups across sectors such as artificial intelligence, fintech, digital health, consumer technology, and energy. With offices spanning North America, Europe, Asia, and Latin America, it leverages a global network to support founders in scaling their ventures internationally. In 2025, Cathay Innovation launched its largest fund to date—Fund III, a $1 billion investment vehicle focused on AI startups. The fund targets application-layer innovations in digital health, consumer apps, fintech, and energy/mobility. Strategic LPs include leading corporates such as Sanofi, TotalEnergies, and BNP Paribas Cardif, reinforcing the firm’s strong links between venture investment and corporate innovation. The firm invests from Series A to late-stage rounds with check sizes ranging from $5 million to $80 million. Already backing 14 companies through Fund III, including Nabla and Mogic AI, Cathay Innovation unites startups, investors, and corporates to deliver strategic growth. Its hybrid global-local model ensures unique market access and operational support to portfolio companies worldwide.

Founded in 1998, Charlesbank Capital Partners is a private equity firm headquartered in Boston, Massachusetts. The firm was established following a spin-out from Harvard Management Company, where its founders managed the endowment’s direct private equity investments. Since its inception, Charlesbank has focused on investing in middle-market companies, leveraging its deep industry expertise and collaborative approach to drive growth and value creation. Charlesbank employs a flexible investment strategy, providing capital for management-led buyouts, growth financings, and opportunistic credit investments. The firm targets businesses across various sectors, including business and consumer services, healthcare, industrial, and technology. By partnering with skilled management teams, Charlesbank aims to build companies with sustainable competitive advantages and strong growth prospects. With offices in Boston and New York, Charlesbank manages a diverse portfolio of companies, primarily in the United States and the United Kingdom. As of March 31, 2025, the firm has approximately $24 billion in assets under management and a team of over 180 professionals dedicated to supporting its investment activities.

ECP Growth, previously operating as Emil Capital Partners, is a private equity firm that adopts a thematic approach to investing. The firm targets companies within resilient categories, emphasizing those with attractive growth fundamentals. By focusing on sectors that demonstrate consistent demand and scalability, ECP Growth seeks to build a diversified portfolio that can withstand market fluctuations. The firm's investment strategy involves identifying and partnering with businesses that have a clear path to growth, strong leadership, and a competitive edge in their respective markets. ECP Growth provides not only capital but also strategic support to help these companies achieve their full potential. This hands-on approach ensures alignment of interests and fosters long-term partnerships. With a team of experienced professionals, ECP Growth leverages its industry knowledge and network to source and manage investments effectively. The firm's rebranding from Emil Capital Partners to ECP Growth reflects its renewed commitment to identifying and nurturing growth-oriented businesses in today's dynamic economic landscape.

Frist Cressey Ventures is a Nashville-based venture capital firm founded in 2016 by former U.S. Senate Majority Leader Bill Frist, M.D., and entrepreneur Bryan Cressey. From early on, the firm has pursued a mission to transform healthcare through strategic investments in innovative companies committed to improving patient outcomes and systemic quality of care. At the heart of their approach is a values-driven partnership model rooted in reliability, integrity, and a hands-on drive to create meaningful impact. The firm specializes in seed and early growth stage investments in technology and services that enhance care coordination, operational efficiency, and population health. Portfolio interests span health-tech software, InsurTech, direct care models, AI-powered clinical solutions, and consumer health platforms. Known for its deep domain expertise, FCV offers more than just capital: it provides sector insight, executive networks, and operational support to help entrepreneurs build scalable, value-based healthcare ventures. With more than 60 investments and notable partners like Monogram Health, Praia Health, CodaMetrix, Carta Healthcare, and Bicycle Health, FCV has built a brand as a trusted investor in the U.S. healthcare innovation ecosystem. Managing over USD 400 million in assets and currently pursuing a USD 400 million Fund IV, the firm maintains a laser focus on healthcare transformation through high-growth ventures led by visionary and mission-aligned founders.

Greenoaks Capital is a global investment firm headquartered in San Francisco, California, specializing in long-term, concentrated investments in technology-enabled businesses. Founded in 2012 by Neil Mehta, the firm partners with visionary entrepreneurs to build enduring companies that define their industries. Greenoaks focuses on identifying businesses with strong unit economics and sustainable competitive advantages. The firm has a diversified portfolio that includes notable companies such as Robinhood, Stripe, Coupang, Deliveroo, Flipkart, and Wiz. Greenoaks' investment strategy emphasizes patience and a deep understanding of the businesses it invests in, allowing for meaningful contributions to their growth and success. By maintaining a concentrated portfolio, the firm ensures dedicated support to each of its investments. Greenoaks operates with a global perspective, investing across North America, Europe, Asia, and other regions. The firm's approach is characterized by a commitment to long-term partnerships, data-driven decision-making, and a focus on building companies that have the potential to become market leaders. With a team of experienced professionals, Greenoaks continues to seek out opportunities to support transformative businesses worldwide.

HealthBridge Innovation Partners is a U.S.-based growth equity firm focused on investing in healthcare companies at critical inflection points — when revenue is scaling, unit economics are proven, and companies are preparing for strategic exits or buyout interest. Co-founded by Fazeela Abdul Rashid and Richard Pines, HealthBridge brings a differentiated approach that blends capital with operational expertise to accelerate profitability rather than merely subsidize growth. The firm concentrates on three core verticals: healthcare information technology, digital health, and medical products with defensible intellectual property. Its strategy is built around partnering with later-stage innovators who have already achieved product-market fit but require support to scale sustainably. Through structured equity and credit solutions, HealthBridge aims to generate asymmetric returns while preserving downside protection. HealthBridge is backed by a strategic seed commitment from an institutional platform that supports emerging managers. This partnership gives the firm access to a tailored program offering firm-building support, business development tools, and operational templates. Positioned at the intersection of healthcare transformation and private capital innovation, HealthBridge is poised to become a value-added partner to growth-stage companies navigating complex markets and scaling challenges.

Founded in 2019 and headquartered in Munich, Germany, Hitachi Ventures is the global corporate venture capital (CVC) arm of Hitachi Group. Operating as a standalone, return‑driven fund with Hitachi as its sole limited partner, the firm focuses on building partnerships with visionary founders to drive breakthrough innovation across climate, health, digital and industrial sectors. With offices in Munich, Boston and Palo Alto, Hitachi Ventures invests globally in startups aligned with Hitachi’s mission of social innovation. Under the leadership of CEO & Managing Director Dr. Stefan Gabriel—who founded the CVC and brings over 20 years of venture and corporate innovation experience—the firm invests in early to mid‑stage startups (primarily pre‑seed to Series B/C). Hitachi Ventures provides both capital and strategic alignment with Hitachi’s business units, enabling collaboration and scale opportunities across industry, digital, environment and healthcare domains. The firm currently manages four funds, including Fund IV launched in February 2025 with a commitment of $400 million, bringing total assets under management to approximately $1 billion. Hitachi Ventures seeks startups primarily in Europe, Israel and North America, targeting areas like Industry 5.0, TechBio, AI/data infrastructure, circular economy solutions, decarbonization and frontier deep‑tech.

Insight Partners is a global growth‑stage investor that focuses exclusively on software and technology‑enabled businesses. Since its founding in 1995, the New York‑headquartered firm has deployed capital across more than 800 companies worldwide and guided over 55 of them to public offerings. With more than US$90 billion under management, Insight invests at every stage from minority growth rounds to majority buyouts, but always with an eye toward helping founders scale efficiently. The firm’s Onsite program provides portfolio companies with a dedicated team of operators, marketers, engineers and talent specialists who help drive product development, revenue growth, sales effectiveness and executive hiring. Insight’s portfolio spans vertical and horizontal software, cybersecurity, fintech, data analytics and digital infrastructure across North America, Europe, Israel and Asia. Unlike many investors, the firm is comfortable writing very large checks and often leads financing rounds. Insight prioritizes partnership, often remaining involved for years as companies expand into new markets or prepare for IPOs. Its culture blends analytical rigor with entrepreneurial empathy, rooted in the belief that enduring software companies are built through disciplined execution, customer obsession and continuous innovation.

JMI Equity is a growth equity firm that partners with leading software companies. Founded in 1992, JMI has invested in over 190 businesses, including more than 100 cloud investments, and has completed over 120 exits. The firm's portfolio companies collectively generate $10 billion in revenue and represent $80 billion in enterprise value, employing over 36,000 people. With offices in Baltimore, San Diego, and Washington, D.C., JMI Equity provides flexible capital, strategic guidance, and operational support to help companies scale and build lasting value. The firm typically invests between $25 million and $250 million in companies with proven business models, high recurring revenue, and long-term growth potential. JMI Equity focuses on sectors such as cloud computing, energy, utilities, real estate, education, finance, insurance, legal, government, digital health, and information technology, primarily targeting companies in North America and Europe.

Lightspeed Venture Partners is a global venture capital firm founded in 2000, specializing in multi-stage investments across enterprise, consumer, fintech, and healthcare sectors. With a mission to accelerate disruptive innovations, Lightspeed has backed over 500 companies worldwide, including notable names like Snap, Affirm, and Nutanix. The firm's collaborative approach and deep industry expertise have positioned it as a trusted partner for entrepreneurs aiming to build impactful businesses. Operating from 14 offices across the United States, Europe, Asia, and Israel, Lightspeed maintains a strong global presence. This extensive network enables the firm to identify and support promising startups in diverse markets. By providing not only capital but also strategic guidance, Lightspeed helps its portfolio companies navigate the challenges of scaling and innovation. As of 2025, Lightspeed manages approximately $28.2 billion in assets under management, reflecting its significant role in the venture capital landscape. The firm's commitment to fostering innovation and long-term partnerships continues to drive its success in supporting the next generation of industry leaders.