Charlesbank funds HBox to scale virtual specialty care solutions.

Charlesbank Capital Partners has agreed a growth investment to accelerate the expansion of HBox, the Boston-based virtual care platform focused on specialty practices. The capital will support product development, wider clinical deployment and commercial scale-up as specialty clinics look to extend care beyond the four walls of the hospital.

HBox was co-founded and is led by Banu Dhanakoti (Chief Executive Officer), Sandeep Subramanya (Chief Operating Officer) and Mohammed Ali (Chief Revenue Officer). The company’s offering combines cloud software, connected devices and patient engagement services to create a “virtual clinic within a clinic” for cardiology, pulmonology, nephrology and other specialty areas. HBox aggregates real-time vitals, patient-reported actions and clinical notes into a single clinician-facing workflow designed to manage large chronic populations efficiently.

Investors are moving into virtual specialty care as reimbursement models shift toward outcomes and continuous care. Remote patient monitoring and virtual care adoption have seen sustained double-digit annual growth, driven by rising chronic disease prevalence and stronger payer coverage for monitoring programs. Charlesbank’s Technology Opportunities Fund II — part of Charlesbank Capital Partners — will provide the funding to accelerate HBox’s roadmap amid that market tailwind.

“This capital enables us to deepen clinical integrations and broaden access for high-risk patients,” said Banu Dhanakoti. She added that rapid, personalized monitoring can cut avoidable hospital visits for cardiac patients and improve day-to-day disease management for families and clinicians without adding operational burden to clinics.

Representatives of Charlesbank framed the deal as strategic: Michael Zirngibl, Principal, highlighted the pairing of software and specialty-focused services as a scalable infrastructure play for outpatient care. Hiren Mankodi, Co-Head of the Technology Opportunities team, noted that many independent specialty practices lack the staff or systems to run remote programs and that HBox fills that gap with an off-the-shelf operating model.

For specialty practices, the immediate benefits are practical: better longitudinal data, fewer in-person escalations and workflows that preserve clinicians’ time. For investors and operators, HBox’s model taps two intersecting trends — the shift to value-based care and the growing acceptance of remote monitoring as a standard of care. Comparable growth-stage investments across digital health underline continued appetite for platforms that combine technology and services.

The transaction was completed on December 17, 2025. Advisors on the deal were disclosed by the parties. Looking forward, the funding positions HBox to broaden its footprint across independent specialty practices nationwide and to accelerate product features that support population health goals and payer partnerships.