Venture Capital Firms in Mexico

500 Global (formerly 500 Startups) is a global venture capital and accelerator firm founded in 2010 by Dave McClure and Christine Tsai. Headquartered in San Francisco with a global presence, the firm supports founders through accelerator programs, mentorship, and capital. The firm manages approximately US $2.3 billion in assets and has backed over 5,000 founders across more than 2,500 startups in over 80 countries. Its portfolio includes more than 30 unicorns and many high-growth companies exceeding US $100 million in valuation. 500 Global specializes in early-stage investments across sectors such as fintech, AI, SaaS, e-commerce, health-tech, and enterprise software. Through programs like its flagship accelerator and VC Unlocked, it equips founders and emerging investors with the knowledge, networks, and tools needed to scale globally.

a16z speedrun is an intensive 12-week accelerator program launched by Andreessen Horowitz in 2023, designed to support early-stage founders globally. The program invests up to $1 million in new startups, primarily at the pre-seed and seed stages, with a focus on helping them achieve product-market fit rapidly. It provides direct investment, extensive fundraising support, and connections to a vast network of external investors.The program was established in 2023 by Andreessen Horowitz, a prominent American venture capital firm founded by Marc Andreessen and Ben Horowitz in 2009. Initially, a16z speedrun focused on pre-seed gaming startups, drawing its name from the gaming term "speedrunning" to reflect its emphasis on rapid development. The firm later expanded its scope to encompass a broader range of technology and entertainment startups, including those in AI and creative industries, while maintaining its core ethos of fostering innovation and accelerating growth.Since its inception, a16z speedrun has rapidly scaled, deploying over $180 million to fund more than 150 startups. Notable portfolio companies mentioned include Sekai, Fundamental Research Labs, and k-ID, all of whom have lauded the program's impact on their growth, from securing talent and early design partners to strategic guidance and successful fundraising rounds. The program culminates in a Demo Day, where founders present to a large audience of investors.The a16z speedrun program offers comprehensive coaching and mentorship, including 1:1 sessions with industry leaders and the a16z speedrun team. Key individuals involved include Jon Lai, an integral part of the speedrun team, and Andreessen Horowitz partners like Joshua Lu and Andrew Chen, who provide strategic guidance and mentorship. The program also leverages the broader expertise and network of Andreessen Horowitz, with founders Marc Andreessen and Ben Horowitz participating as speakers and mentors, offering unparalleled access to seasoned operators and a vast ecosystem of resources.

Axon Partners Group is a global investment and consulting firm that focuses on technology and innovation. The firm operates with a dual approach, offering both investment management and strategic consulting services. They partner with visionary leaders to drive innovation and create value in the technology sector, while their consulting arm provides insights and expertise for strategic, commercial, policy, and investment decisions. Axon Partners Group emphasizes effective strategies and investments to leverage innovative technologies for a better world.Founded in 2006 by Francisco Velázquez, Axon Capital and SVP Advisors initially operated as two separate entities in Madrid. Axon Capital focused on tech transfer venture capital, aiming to extract value from university technologies in Spain, and secured its first tech transfer VC fund in July 2007. SVP Advisors, on the other hand, extended Velázquez's consulting experience internationally. In 2012, Axon Capital and SVP Advisors merged to form Axon Partners Group, expanding their team and global reach. The firm successfully completed an IPO and was listed on the Madrid Stock Exchange, raising approximately €12 million.Axon Partners Group has a diverse portfolio with investments in various technology-driven companies. Recent investments include Dynamics VR, ISAAC (Construction and Engineering), and Grodi (Agriculture). The firm has also invested in companies like Taalentfy, a technology platform for employability and career guidance, and Odders, an XR company specializing in virtual reality games and applications. Other notable investments include Metricool, Instaleap, and W•SENSE. Axon Partners Group has also made 43 exits, with its latest being from Dogfy Diet in October 2025.The firm's team comprises over 100 seasoned professionals across its Consulting and Investment divisions, with diverse backgrounds and nationalities. This international team combines multi-sector tech expertise with a proven investment and advisory track record, aiming to deliver the agility of a boutique firm with the capabilities of a global company. Key management includes Francisco Velázquez as Chairman and Managing Partner, and Alfonso de León and Dimitri Kallinis as Managing Partners and Board Members.

Dalus Capital is a leading venture capital firm based in Mexico, focused on investing in innovative, high-growth companies that leverage technology to address major challenges in Latin America. The firm backs visionary entrepreneurs building scalable solutions in fintech, edtech, healthtech, climate tech, and digital transformation. Dalus aims to generate both strong financial returns and measurable social and environmental impact. The firm typically invests in early to growth-stage companies with proven business models and strong management teams. Dalus supports its portfolio with strategic guidance, operational expertise, and access to an extensive network across the region. With a disciplined investment approach, Dalus targets businesses that can drive systemic change and create inclusive opportunities for underserved populations. Since its founding, Dalus Capital has established itself as a key player in the Latin American VC ecosystem, managing multiple funds and maintaining a strong presence in Mexico and across the region. The firm continues to champion innovation and entrepreneurship as a force for sustainable development and long-term value creation.

G Squared is a global venture capital firm specializing in growth-stage technology investments. Founded in 2011 and headquartered in Chicago, with offices in San Francisco, Zurich, and Miami, the firm focuses on providing both primary and secondary capital to dynamic private companies. G Squared's investment strategy addresses the evolving needs of venture-backed companies that remain private longer, offering liquidity solutions to early investors and employees while supporting ongoing growth. The firm's portfolio includes high-profile companies such as Airbnb, Spotify, Snapchat, and Twitter, reflecting its commitment to backing transformative businesses across various sectors. G Squared employs a unique combination of quantitative analysis and deep sector expertise to identify and invest in companies that leverage technology to improve lives and disrupt industries. Their approach encompasses investments in both primary funding rounds and the secondary market, acquiring existing shares from stakeholders seeking liquidity. With a concentrated portfolio and a track record of delivering strong returns, G Squared has established itself as a leading venture capital firm in the technology sector. The firm's strategic investments and hands-on support aim to drive value creation and long-term success for its portfolio companies. G Squared's commitment to innovation and adaptability positions it as a trusted partner for companies navigating the complexities of growth and market expansion.

NewHealth Ventures is a venture capital firm positioned as the first LATAM-based VC fund focused exclusively on disruptive, yet clinically validated, medical technologies from around the world. The firm combines a strong financial return mandate with a deep commitment to human impact, backing companies that not only scale successfully but also significantly improve patient outcomes and healthcare delivery.The fund's investment thesis centers on medical technology companies that are already clinically validated and poised for commercial growth. NewHealth Ventures leverages a network of strategic Limited Partners within the LATAM healthcare ecosystem, who provide not only capital but also critical access to local markets, providers, and talent. This strategic positioning enables portfolio companies to expand into Latin America while benefiting from deep healthcare domain expertise.NewHealth Ventures co-invests alongside top-tier venture capital firms in the United States, Europe, and Israel, gaining access to exclusive deals while deploying a fraction of the capital. This model allows the fund to retain economic and board representation benefits while focusing on high-conviction opportunities in medtech and healthtech. The firm is led by experienced healthcare investors and operators, including Managing Partners Mario Nissan, Alfonso de Robina, and Nathan Shabot, supported by a team of healthcare entrepreneurs, advisors, and investment professionals.