Venture Capital Firms in California

111° West Capital is a multi-stage investment firm that partners with commercial-stage enterprise software companies focused on transforming healthcare delivery and operations.The firm combines a dedicated investment team with an Operator network to provide a hands-on, growth-oriented approach intended to accelerate revenue, scale operations and drive successful exits for portfolio companies.111° West Capital’s public materials and industry profiles indicate a primary focus on digital health and enterprise healthcare software investments, and that the firm was founded in 2021 and is active across stages from commercial growth rounds through Series A/B in its areas of expertise.

137 Ventures is a San Francisco‑based private investment firm specializing in providing liquidity solutions and growth capital to founders, early employees and angel investors in high‑growth technology companies. Founded in 2011, the firm manages over US$5 billion across funds that purchase private company shares on the secondary market and participate in primary growth rounds. 137’s approach allows early stakeholders to realize liquidity without forcing a premature sale or IPO, while enabling companies to continue compounding value privately. Its portfolio includes some of Silicon Valley’s most iconic names in enterprise software, fintech, consumer internet and mobility. In addition to capital, the firm offers strategic support, including introductions to later‑stage investors, guidance on secondary market dynamics and advice on navigating complex cap‑table structures. The team maintains strict confidentiality and aims to align with both founders and early shareholders by structuring transactions that work for all parties. 137 Ventures’ culture emphasizes long‑term thinking, integrity and the belief that providing liquidity at the right time can be a catalyst for innovation, allowing founders and employees to focus on building rather than managing personal finances.

1984 Ventures is a venture capital firm founded in 2017 and headquartered in San Francisco, California. Inspired by Apple’s iconic “1984” Macintosh launch, the firm champions the belief that nimble, software-driven startups can challenge and transform industry incumbents. The firm invests primarily at the pre-seed and seed stages, focusing on founders with grit, industry insights, and strong engineering culture. 1984 Ventures operates with a collaborative, founder-friendly approach, typically investing via SAFE or equity without taking board seats. The firm provides hands-on support in recruiting, fundraising, and preparing portfolio companies for successful Series A rounds. It also publishes a public Founders Handbook to guide early-stage teams on topics ranging from cap tables to Series A preparation and open-source strategy. The firm’s portfolio includes over 120 investments, with notable companies such as Fairmarkit, Reggora, BuildOps, Convex, Kyte, and PadSplit. 1984 Ventures has achieved multiple exits and continues to back innovative startups across sectors like SaaS, AI, fintech, proptech, logistics, and healthcare, with a strong presence in the United States and selective investments in Europe and Latin America.

1Flourish Capital is a venture capital firm focused on investing in early-stage, disruptive technology startups led by founders of high character who are on missions to advance human flourishing. Beyond providing capital, 1Flourish actively supports its portfolio companies through strategic guidance, leadership training, and cultivating exceptional company cultures based on principles such as trust, humility, and accountability. Their approach emphasizes building enduring values and sustainable success in their investments. The firm leverages the expertise of advisors like Patrick Lencioni and The Table Group to help founders develop strong leadership and governance practices. 1Flourish’s team has extensive experience managing over $1 billion in venture capital and private equity, with backgrounds including serial entrepreneurship, technology leadership, and operational excellence. This deep operational and investment experience enables them to nurture portfolio companies effectively. 1Flourish primarily invests in the United States, focusing on sectors such as e-commerce and enterprise technology. Their investment style is collaborative and operator-led, emphasizing disciplined scaling of innovative businesses. The firm is known for its commitment to principled leadership and high-performance company cultures, aiming to back visionary technical founders poised to scale solutions that enhance human well-being.

47th Street Partners is a venture capital firm headquartered in Menlo Park, California, focused on investing in early-stage and seed rounds of emerging technology companies. The firm actively participates in the tech startup ecosystem, providing capital and strategic support to innovative ventures.47th Street Partners emphasizes partnerships with founders and companies that leverage technology to drive growth and transformation. The firm is known for leading investments in technology sectors and has a particular interest in Government Technology (GovTech), artificial intelligence (AI), and software solutions.Founded in 2022 as a Limited Partnership, 47th Street Partners combines deep industry knowledge with a hands-on approach, seeking to help portfolio companies scale effectively. While specific details on assets under management and employee count are not publicly disclosed, the firm's active role in seed and venture rounds highlights its focus on early-stage innovation.The firm’s registered name is 47th Street Partners I-a LP, established in Menlo Park, CA.

500 Global (formerly 500 Startups) is a global venture capital and accelerator firm founded in 2010 by Dave McClure and Christine Tsai. Headquartered in San Francisco with a global presence, the firm supports founders through accelerator programs, mentorship, and capital. The firm manages approximately US $2.3 billion in assets and has backed over 5,000 founders across more than 2,500 startups in over 80 countries. Its portfolio includes more than 30 unicorns and many high-growth companies exceeding US $100 million in valuation. 500 Global specializes in early-stage investments across sectors such as fintech, AI, SaaS, e-commerce, health-tech, and enterprise software. Through programs like its flagship accelerator and VC Unlocked, it equips founders and emerging investors with the knowledge, networks, and tools needed to scale globally.

8VC is a technology and life‑sciences venture capital firm founded in 2015 by Joe Lonsdale, Drew Oetting, Alex Kolicich, and Jake Medwell. Originating in San Francisco and now headquartered in Austin, Texas, the firm brings together operators, technologists, and policy thinkers to invest in startups built to solve deep infrastructure and societal challenges. With over $6 billion in committed capital and a portfolio of more than 350 companies, 8VC invests across pre‑seed through growth stages in areas such as logistics, defense, enterprise software, healthcare, life sciences, manufacturing, financial services, and IT infrastructure. The firm also operates a proprietary “Build” program to launch new companies and a fellowship to attract top talent to its portfolio. Driven by a mission to "fix a broken world," 8VC backs transformative entrepreneurs building long‑term value in sectors often overlooked or deeply entrenched. Notable investments include Anduril, Epirus, Palantir, Guardant Health, and Hyperloop One, reflecting the firm’s belief in principled contrarianism and societal impact.

a16z speedrun is an intensive 12-week accelerator program launched by Andreessen Horowitz in 2023, designed to support early-stage founders globally. The program invests up to $1 million in new startups, primarily at the pre-seed and seed stages, with a focus on helping them achieve product-market fit rapidly. It provides direct investment, extensive fundraising support, and connections to a vast network of external investors.The program was established in 2023 by Andreessen Horowitz, a prominent American venture capital firm founded by Marc Andreessen and Ben Horowitz in 2009. Initially, a16z speedrun focused on pre-seed gaming startups, drawing its name from the gaming term "speedrunning" to reflect its emphasis on rapid development. The firm later expanded its scope to encompass a broader range of technology and entertainment startups, including those in AI and creative industries, while maintaining its core ethos of fostering innovation and accelerating growth.Since its inception, a16z speedrun has rapidly scaled, deploying over $180 million to fund more than 150 startups. Notable portfolio companies mentioned include Sekai, Fundamental Research Labs, and k-ID, all of whom have lauded the program's impact on their growth, from securing talent and early design partners to strategic guidance and successful fundraising rounds. The program culminates in a Demo Day, where founders present to a large audience of investors.The a16z speedrun program offers comprehensive coaching and mentorship, including 1:1 sessions with industry leaders and the a16z speedrun team. Key individuals involved include Jon Lai, an integral part of the speedrun team, and Andreessen Horowitz partners like Joshua Lu and Andrew Chen, who provide strategic guidance and mentorship. The program also leverages the broader expertise and network of Andreessen Horowitz, with founders Marc Andreessen and Ben Horowitz participating as speakers and mentors, offering unparalleled access to seasoned operators and a vast ecosystem of resources.

Abstract Ventures is a San Francisco-based venture capital firm with $1.8 billion in assets under management, focusing on seed and early-stage companies. The firm is sector-agnostic, investing in a wide range of industries including biotechnology, consumer products, crypto-blockchain, and enterprise frontier technology. Abstract Ventures is known for its founder-friendly approach, offering not only capital but also extensive connections and strategic support to help portfolio companies succeed.The firm was founded in 2016 by Ramtin Naimi. Naimi began trading tech stocks at age 13 and later founded a hedge fund before transitioning to private market investing. He established Abstract Ventures at the age of 25. The firm's strategy emphasizes a partnership-oriented approach, prioritizing deep relationships with founders over a broad portfolio.Abstract Ventures has made over 500 investments to date, with a portfolio that includes notable companies such as Rippling, Material (which achieved unicorn status in 2022), Solana, WorkOS, and xAI. Their investments span various sectors, including AI & Intelligence (e.g., LangChain, Replit, Cognition), Enterprise Software (e.g., Figma-acquired Dynaboard, Voiceflow), Fintech (e.g., Alpaca, Ripple, Cherry), Healthcare (e.g., Garner, Connie Health), and Frontier Tech (e.g., SpaceX, Halo Industries).The team at Abstract Ventures is spearheaded by founder and General Partner Ramtin Naimi, alongside other partners like Alex Davidov, David Kwon, and Andrei Kozyrev. Caroline Stevenson serves as Operating Partner for Talent, and Anthony Heckman as Operating Partner for GTM. The team leverages years of investment experience and market insight, providing extensive support and mentorship to their portfolio companies.

Accenture Ventures is the corporate venture capital arm of Accenture plc, a global professional services company. Established in 2015, the firm focuses on making strategic investments in early- and growth-stage technology companies. Its primary objective is to identify and partner with startups developing innovative enterprise and industry-focused technologies, integrating their capabilities into Accenture's extensive services and client solutions. This approach emphasizes strategic impact and accelerating product-market fit for its portfolio companies, leveraging Accenture's vast global client base and deep industry expertise.The firm's investment thesis centers on technologies that drive digital transformation and enhance enterprise capabilities. Key areas of focus include artificial intelligence (AI), cloud computing, cybersecurity, blockchain, data and analytics, and digital engineering. Accenture Ventures actively seeks out companies that can provide vertical AI solutions tailored to specific sectors such as financial services, healthcare, manufacturing, retail, and the public sector. They also explore emerging trends like physical AI and robotics, aiming to bridge the gap between groundbreaking ideas and scalable enterprise solutions.Accenture Ventures manages a $250 million fund and has made over 70 active venture investments. Notable portfolio companies include Replit, a platform for developing and deploying applications with AI; Sanctuary AI, a developer of AI-powered general-purpose robots; Open Cosmos, an operator of space missions providing satellite data; and Pixxel, which offers hyperspectral imaging satellites. The firm typically invests in Series A and Series B rounds, supporting startups through various stages of growth.The team at Accenture Ventures includes experienced professionals such as Tom Lounibos, Avnish Sabharwal, and Joe Lui. They bring a wealth of knowledge in technology and venture capital, working closely with portfolio companies to provide not just capital, but also strategic guidance, market access to Fortune Global 500 clients, and opportunities for co-innovation. The firm's global mandate allows it to invest across continents, emphasizing execution and local market understanding to support diverse innovation hubs.

Adverb Ventures is an early-stage venture capital firm that partners with founders to build enduring, breakout companies; the firm emphasizes how companies are built — “the adverbs matter as much as the verbs.”Founded by former operators and investors with product and leadership experience at companies such as Twitter, Slack, and Robinhood, Adverb runs programming and community events for founders and curates an operator-led approach to support portfolio teams.The firm’s portfolio includes companies across AI, enterprise software and consumer technology (examples listed on their site include Cove, Hypernatural, Shotsy, Outset AI and others), and it actively convenes founders through events, retreats and newsletters to deepen founder connections and operational support.

AE Industrial Partners (AEI) is a private equity firm specializing in control investments in aerospace, defense & government services, space, power & utility services, and industrial technology. Founded by experienced industry executives, AEI brings deep operational expertise and strategic resources to its portfolio companies, focusing on accelerating growth, innovation, and long-term value creation. AEI’s investment philosophy centers around partnering with management teams to transform and scale businesses in highly technical and regulated sectors. The firm’s team combines financial acumen with sector-specific insight to identify and build companies that are well-positioned to lead in their markets. AEI typically targets companies with strong engineering capabilities, defensible market positions, and opportunities for operational enhancement or strategic consolidation. With headquarters in Boca Raton, Florida, and offices in Washington D.C. and Los Angeles, AE Industrial Partners is active across North America. The firm manages multiple funds and strategies, including private equity, venture capital, and structured capital solutions, allowing for flexibility across the capital stack. AEI has earned a reputation as a leading investor in the aerospace and defense ecosystem.

Aglaé Ventures is a technology-focused investment firm created to fund and support ambitious founders building fast-growing, asset-light companies. Backed by Agache (formerly Groupe Arnault), the principal investment vehicle of Bernard Arnault, it operates from Paris with offices in New York and San Francisco. The firm invests broadly across stages — from seed and Series A through Series B to pre-IPO — and deploys ticket sizes from approximately €100K (seed) up to €100M (growth/pre-IPO), targeting marketplaces, software (SaaS and open-source), content and consumer platforms, developer and app tools, and digitally native vertical brands among other asset-light models. Aglaé emphasizes long-term capital, operational support (growth management, brand building, digital marketing, and global expansion), and access to an extensive network including the LVMH ecosystem and global tech founders and investors to help portfolio companies scale globally.

AICONIC Ventures is a venture capital firm specializing in early-stage investments across artificial intelligence (AI) and deep technology. The firm focuses on groundbreaking innovations from Pre-seed to Series B, with a strategic emphasis on bridging the technological advancements emerging from the US, particularly Silicon Valley, with global markets, especially in Asia. Their investment thesis centers on identifying and nurturing category-defining AI companies that are highly technical and driven by deep research, aiming to help these startups achieve global scale and reach through their extensive network of customers and investors in Asia.Founded in 2025, AICONIC Ventures was launched by Mukaya (Tai) Panich, who serves as the CIO and Managing Partner. Panich brought over 20 years of experience in the technology sector and previously led SCB 10X, a corporate venture capital fund, for over five years. The firm was established with an initial fund close of $200 million, with a target of $250 million, and aims to capitalize on the ongoing fourth industrial revolution driven by generative AI.The firm's portfolio showcases a diverse range of innovative companies, including Corintis, which focuses on bio-inspired in-chip cooling, Sophont, a developer of state-of-the-art pathology foundation models, and eBots, a company enabling viable and competitive onshoring manufacturing in the US. Other notable investments span areas such as novel power management ICs for AI data centers, versatile robots for adaptive manufacturing, next-generation photonics, autonomous AI agents, game-changing liquid cooling for AI chips, preemptive cybersecurity, and universal multimodal foundation models for healthcare.The AICONIC Ventures team comprises seasoned professionals with deep technical and business expertise. Mukaya (Tai) Panich, with her background in semiconductor startups and extensive investment experience, leads the firm. Advisors like Lip-Bu Tan, former CEO of Intel and founding managing partner of Walden Catalyst, and Amarjit Gill, a co-founder of multiple successful tech companies acquired by industry giants, provide invaluable guidance. The team also includes Thanapong (Mod) Boontaeng as CTO, focusing on technical due diligence and AI tech stack evaluation, and Kaweepol (Kevin) Panpheng as Partner, bringing quantitative rigor to deal evaluation.

Alexandria Venture Investments is the strategic venture capital arm of Alexandria Real Estate Equities, Inc., a leading developer of life science and technology campuses. With deep roots in the biotech and healthcare sectors, the firm invests in transformative early- to growth-stage companies that are shaping the future of life sciences, diagnostics, digital health, and agtech. The firm leverages its unique position within Alexandria's ecosystem to provide more than just capital—it offers access to cutting-edge facilities, industry expertise, and a vast network of scientific and corporate leaders. Alexandria Venture Investments is known for its active partnership model, working closely with founders and management teams to accelerate innovation and growth. Focused on advancing solutions that address critical global health challenges, the firm targets companies with strong scientific foundations and scalable platforms. Its portfolio includes some of the most promising startups and industry leaders across North America and select global markets.

Almaz Capital is a global venture capital fund that invests in early-stage, capital-efficient technology companies operating in high-growth sectors. The firm primarily targets disruptive deep tech within the B2B software space, with a keen interest in areas such as Artificial Intelligence (AI), Machine Learning (ML), blockchain applications, the Internet of Things (IoT), edge computing enablers, and cybersecurity. Their investment strategy is designed to bridge companies from emerging tech regions to the global marketplace, fostering their growth and international expansion.Almaz Capital was founded in 2008 by Alexander Galitsky, Charles Emmitt Ryan, Peter Loukianoff, and Pavel Bogdanov. The firm was initially backed by Cisco Systems and the European Bank for Reconstruction and Development (EBRD) with the vision of connecting Eastern European startups, particularly those from the CIS and CEE regions, with the resources and network of Silicon Valley. This "bridge fund" model aimed to leverage engineering talent in Eastern Europe for global markets. Over time, the firm's geographical focus has evolved, shifting its European operations to Berlin in 2017 and ceasing investments with ties to Russia in 2014 and Belarus in 2020, while remaining committed to supporting Ukrainian startups.Almaz Capital has built a diverse portfolio of approximately 50 companies, with over $300 million invested. Notable exits include Yandex (IPO NASDAQ), Qik (acquired by Skype), Sensity Systems (acquired by Verizon Communications), and Acumatica (acquired by EQT). Recent investments span various industries, including Business/Productivity Software (Moonshot AI, Platma, specter automation, Dabbl, MakeTime, Cinarra), Specialty Retail (Refurbed), Hardware (USound, Minut), Database Software (ClickHouse), and other technology areas like 3DLOOK (AI-first mobile body measuring), DMarket (NFT trading platform), and Mobalytics (gaming).The Almaz Capital team comprises experienced general partners and operational staff with diverse backgrounds in investment, operations, enterprise software, telecom, security, networking, analytics, data technologies, fundraising, LP relations, and portfolio management. Key team members include Alexander Galitsky (Co-Founder and Managing Partner), Charles E. Ryan (General Partner focusing on later-stage companies and exit strategy), Aniruddha Nazare (General Partner based in Berlin with expertise in enterprise software and telecom), Geoffrey Baehr (General Partner with a deep technical focus on security, networking, analytics, and data technologies), and Pavel (Pasha) Bogdanov (General Partner based in Berlin, involved in fundraising and portfolio management). Michael Bastholt serves as Partner & COO, overseeing operational leadership and investor relations, while Russell Green is the Financial Controller. Daniil Stolyarov and Tanya Dadasheva also contribute as partners and managing directors, respectively.

Amboy Street Ventures is the world’s first venture capital fund dedicated exclusively to Women’s Health and Sexual Wellbeing for all genders. Founded in 2020 and headquartered in Los Angeles, California, the firm focuses on investing in innovative startups that address critical but underserved areas such as fertility, menopause, maternal health, LGBTQ+ health, menstruation, hormonal health, sexual health, and contraception. The fund targets the untapped $1 trillion global women’s health market by supporting cutting-edge technologies and products that improve health outcomes and wellbeing.The firm primarily invests in Seed and Series A rounds, backing companies that are advancing the industry in America and Europe. Amboy Street Ventures is an active investor that adds value beyond capital through its Value Enhancement Team, which supports portfolio companies in marketing, branding, sales, product development, scientific innovation, and public education. Their portfolio includes diverse startups such as Evvy (vaginal microbiome care), Contraline (non-hormonal male birth control), HeyJane (digital abortion clinic), and Millie (modern maternity clinics).Amboy Street Ventures was founded by Carli Sapir, who leads the investment team and brings a personal passion for women’s health innovation. The team includes partners with expertise in private equity, medicine, sexual health, and marketing. The fund is named after the historic Amboy Street Birth Control Clinic in Brooklyn, symbolizing its commitment to advancing accessible and inclusive health solutions. With a focus on health equity and social reformation, Amboy Street Ventures aims to bridge the funding gap that has historically limited innovation in women’s and sexual health sectors.

Andra Capital is a premier evergreen technology growth fund headquartered in San Francisco, focused on multi-stage investments in high-potential private technology companies, particularly those in growth and late-stage phases targeting pre-IPO opportunities. The firm supports visionary founders and management teams through a curated portfolio approach, leveraging deep domain expertise, operational experience, and extensive networks to drive superior returns and accelerate technological evolution.The team's philosophy centers on five core investment principles to identify exceptional companies with enduring technology moats and scalable business models resilient to macroeconomic cycles. Andra emphasizes funding disruptive technologies that challenge incumbents and enable new business models in an intelligent, connected digital age, with investments spanning enterprise software and other tech sectors representing over $100B in value and 100+ transactions.As an open-end and closed-end fund manager founded in 2016, Andra Capital provides investors access to Silicon Valley's private tech ecosystem with shorter exit horizons (2-3 years for late-stage) and a portfolio strategy balancing high returns with risk mitigation through diversification.

Anorak Ventures is a seed-stage venture capital firm established in 2016, with offices located in Los Angeles and San Francisco. The firm focuses on investing in pre-seed and seed stage companies that are developing differentiated and disruptive technologies. Anorak Ventures aims to assist these early-stage companies in achieving product-market fit and securing subsequent rounds of financing. The firm has built a substantial portfolio, having invested in over 120 seed-stage technology companies that collectively represent an aggregate market capitalization of $125 billion.The firm's investment thesis, termed "Computing in the Third Dimension," centers on the convergence of several key technological areas. These include computer vision, robotics, virtual and augmented reality (VR/AR), and generative artificial intelligence. Anorak Ventures seeks out highly specialized teams, often referred to as "Anoraks," who possess a strong, sometimes obsessive, interest and deep expertise in niche technical subjects relevant to the fund's focus. They are particularly interested in companies that are tackling tough, complex problems at the intersection of the digital and physical worlds, including hardware-enabled services and advanced manufacturing.Anorak Ventures was founded by Greg Castle, who serves as the Managing Partner. Castle brings a background as an entrepreneur and corporate marketer, with a significant track record in venture investing. He has been involved with over 150 seed-stage companies, with eight of these achieving unicorn status, including notable names like Oculus, Flexport, Anduril, Mux, Onebrief, Flock Safety, Sesame, and Rec Room. In July 2024, Charlie Leggate joined the team as a Partner, further strengthening the firm's expertise in deep tech and frontier technologies. Amal Dorai is also listed as a Partner.The firm has actively raised funds, closing its debut fund at $13.5 million in 2017 and currently investing from its second fund, which has a target of $25 million. A first close for Fund 3 was scheduled for Q4 2024. Recent investments include Arinna, a space power startup, and ZeroTier, a software-defined networking company. Anorak Ventures' portfolio spans various innovative companies, reflecting its commitment to transformative technology across diverse sectors.

Anthos Capital is a venture capital firm headquartered in Santa Monica, California, founded in 2007 by Bryan Kelly and Paul Farr. The firm specializes in partnering with exceptional entrepreneurs to build category-defining companies, focusing on early-stage and growth-stage investments in sectors such as technology, healthcare, consumer products, business services, financial services, and education. Anthos Capital is known for providing not only capital but also strategic guidance and operational support to help portfolio companies scale and achieve market leadership. The firm invests in companies that demonstrate strong leadership, scalable business models, and a clear path to sustainable growth. Anthos Capital’s investment themes include consumer dislocation, data and analytics, e-commerce enablement, and enterprise software. The firm actively supports its portfolio companies by leveraging its network and expertise to accelerate growth and create long-term value. Anthos Capital has a diverse portfolio of over 60 investments, including notable companies such as Dollar Shave Club, CloudBeds, DevZero, Railsr, and Yummy.