Wireframe Ventures

Wireframe Ventures is an early-stage venture capital firm that invests in technology companies aiming to build a healthier and more sustainable future. The firm focuses on founders who are harnessing biology to engineer better products, creating scalable solutions to climate change, deploying AI and automation to empower individuals, delivering personal and proactive healthcare, and developing zero-carbon transportation. Wireframe Ventures typically makes initial investments ranging from $500,000 to $2 million at the Pre-seed or Seed stage, and actively supports its portfolio companies through to their institutional Series A funding rounds.

The firm was co-founded in 2016 by Paul Straub and Harsh Patel, who serve as Managing Directors. They established Wireframe Ventures with a core belief that climate and health are deeply intertwined themes offering significant societal impact and extraordinary economic opportunities. The firm emphasizes a hands-on approach, providing capital, time, and belief to accelerate the success of driven founders. They aim to meet founders where they are, offering empathetic listening, honest feedback, and direct support.

Wireframe Ventures boasts a diverse portfolio of notable companies. Key investments include Enveda Biosciences, which focuses on discovering new medicines; Mammoth Biosciences, a leader in CRISPR-based gene editing therapies; Xcimer Energy, developing laser-driven nuclear fusion; and LevelTen Energy, expanding clean energy marketplace services. Other significant portfolio companies include Cocoon, pioneering sustainable construction materials; Great Sky, innovating AI hardware; Recurrent, transforming the used EV market; MycoWorks, creating biomaterials; Electriphi, providing EV fleet charging solutions; and SPAN, offering home and vehicle electrification products.

The investment team, led by co-founders Paul Straub and Harsh Patel, also includes Partner Lily Bernicker. The firm prides itself on its deep domain expertise and networks across its thematic areas, built through years of experience as both investors and operators. They are committed to partnering closely with founders from inception, providing strategic guidance and support to help them achieve product-market fit and secure follow-on funding.