Hatch BioFund

Hatch BioFund is a life sciences venture capital firm headquartered in the Philadelphia region, a prominent global biotech hub. The firm specializes in providing early-stage capital to promising life science companies, with a particular focus on those developing therapeutics and vaccines for human use. Hatch BioFund actively invests across various development stages and treatment modalities, including small molecules, cell therapy, and gene therapy, prioritizing capital efficiency, clear development pathways, and experimental medicines that offer significant societal value.

The firm was officially launched in July 2019 as Hatch BioFund Management, LLC, an investment arm of the Pennsylvania Biotechnology Center. It was established to provide seed capital, lab space, business creation services, and guidance to concept-stage entrepreneurs within the PABC incubator and its BioAccelerator program. Hatch BioFund emphasizes a collaborative approach, actively partnering with its portfolio companies and leveraging its extensive network, which includes successful pharmaceutical companies, research institutions, and biotech incubators, to support their growth and strategic objectives.

Hatch BioFund's portfolio includes innovative companies such as ViTToria Biotherapeutics, a clinical-stage immunotherapy company developing novel CAR T cell therapies; Latus Bio, a gene therapy company focused on the central nervous system; Hula Therapeutics, an immunotherapy spinout; and MasterSwitch Bio, which is developing modified mRNA therapy for End Stage Liver Disease. The firm also invested in Ladder Bio, a company developing a novel chemical platform for highly selective protein binding. These investments highlight Hatch BioFund's commitment to advancing groundbreaking scientific solutions in the life sciences sector.

The team at Hatch BioFund brings deep industry expertise to its investments. Lorenzo Pellegrini, Ph.D., the Managing Partner, has extensive experience as a scientist, investor, and entrepreneur in the life sciences, with a track record of founding and co-founding multiple biotech companies and leading significant venture capital investments. Founders and Advisors Louis P. Kassa III, MPA, and Timothy M. Block, Ph.D., further contribute to the firm's strategic guidance and operational support for its portfolio companies.