Greatpoint Ventures

GreatPoint Ventures is an early-stage venture capital firm specializing in seed and Series A investments across transformative sectors such as enterprise software, healthcare, biotechnology, fintech, food technology, and artificial intelligence. The firm partners closely with founders, making fewer than 10 new investments annually to deliver hands-on operational support drawn from its team's extensive experience building high-value companies. With a focus on revolutionary ideas addressing major industry challenges, GreatPoint Ventures has backed over 116 portfolio companies, including notable successes like Beyond Meat (IPO: BYND) and acquisitions by Salesforce and MoneyLion.

Founded in 2015 by serial entrepreneurs and operators who collectively created $300 billion in enterprise value across 20 companies, GreatPoint Ventures was established to replicate the invaluable support they received from investors during their own ventures. Managing Partners Andrew Perlman and Ashok Krishnamurthi lead the firm, emphasizing a philosophy of 'making no little plans' inspired by architect Daniel Hudson Burnham. Headquartered in San Francisco, the firm manages funds like the GreatPoint Ventures Innovation Fund II ($291.61M) and prioritizes deep involvement in commercialization for seed-stage startups.

The firm's portfolio features standout companies such as Activ Surgical (autonomous surgical robots), Abett (real-time health benefits data), Atlas Health (medical financial aid access), Devoted Health (Medicare insurance), Sirona Medical (radiology OS), and recent investments like Seraphic (browser security, $29M Series A in 2025) and Harmonic ($75M Series A in 2024). Exits include BeyondCore (acquired by Salesforce), Even Financial (acquired by MoneyLion), and Glympse Bio (acquired by SunBird Bio), demonstrating strong returns in healthtech, AI, and consumer sectors.

GreatPoint Ventures' team comprises seasoned operators with over 100 years of combined experience, including Managing Partners Andrew Perlman (co-founder of nine venture-backed firms), Ashok Krishnamurthi, and Gautam Krishnamurthi, alongside General Partner DJ Patil (former U.S. Chief Data Scientist). Partners like Avi Goldberg, Joseph Tuchman, and David Resnekov, plus operational experts such as COO Ashley Sommerschield, bring expertise from telecom, pharma, energy, biotech, and enterprise tech to guide portfolio growth[website].