Amplitude Ventures

Amplitude Ventures is a Canadian venture capital firm founded in 2018 by Dion Madsen and Jean-François Pariseau, former partners at the Business Development Bank of Canada. The firm operates as a full-stack venture capital investor focused on precision medicine companies at the intersection of biology and artificial intelligence. With more than $500 million in assets under management, Amplitude has established itself as a capital catalyst for highly innovative healthcare companies in Canada, deploying a proven venture growth model since its inception that has resulted in over $1 billion in company value creation. The firm's geographic footprint spans multiple Canadian cities with offices in Montreal, Toronto, Vancouver, and Calgary. Amplitude's investment strategy centers on precision medicine, next-generation medical devices, therapeutics, and emerging areas including AI-enabled precision medicine, healthcare IT, and healthcare services. The firm takes a hands-on approach to company building, working with founders as active partners from ideation through patient care. The team combines deep biotech expertise with entrepreneurial experience, having successfully scaled numerous portfolio companies to significant milestones. In May 2024, Amplitude closed its second venture capital fund at $263 million, demonstrating strong investor confidence in the firm's track record and investment thesis. Amplitude's portfolio includes companies addressing critical healthcare challenges through innovative technologies and business models. The firm has supported companies developing precision drug conjugates, AI-powered protein folding platforms, and other differentiated therapeutic approaches. Portfolio companies have achieved notable outcomes including product approvals and successful acquisitions, with founders consistently praising Amplitude's strategic guidance, board involvement, and ability to facilitate connections across the North American investment community. The firm also invests in and mentors early-stage founders through its Amplitude Fellowship program, which brings together Canada's brightest health-focused PhD candidates, postdocs, and MDs to explore biotech concepts and create novel health science companies. The firm's team comprises experienced entrepreneurs and scientists with deep domain expertise in healthcare and life sciences. Amplitude's investment committee and operational team have demonstrated success in building world-class Canadian companies with strong management teams capable of achieving breakout potential. The firm's commitment to transparency, integrity, and excellence has established it as a trusted partner for founders seeking capital and strategic support in the precision medicine space.